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Article

Epigenetic Regulation of CD133 in Gastrointestinal Stromal Tumors

15 Feb 2017

Abstract excerpt

OBJECTIVES: This study ascertained the regulation of the stem cell marker CD133 and its potential applicability for prognostication of gastrointestinal stromal tumors (GISTs). METHODS: A total of 95 resected GISTs were included in the study. CD133 protein expression was assessed immunohistochemically on tissue microarrays. Methylation percentage was quantified by pyrosequencing. Gene expression in cell lines...

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PMID: 28398518
DOI: 10.1093/ajcp/aqx028

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