Prediction of striatal D2 receptor binding by DRD2/ANKK1 TaqIA allele status.

doi:10.1002/syn.21916

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Article

Prediction of striatal D2 receptor binding by DRD2/ANKK1 TaqIA allele status.

Synapse (New York, N.Y.) - 1 Oct 2016

Eisenstein Sarah A, Bogdan Ryan, Love-Gregory Latisha, Corral-Frías Nadia S, Koller Jonathan M, Black Kevin J, Moerlein Stephen M, Perlmutter Joel S, Barch Deanna M, Hershey Tamara

Abstract excerpt

In humans, the A1 (T) allele of the dopamine (DA) D2 receptor/ankyrin repeat and kinase domain containing 1 (DRD2/ANKK1) TaqIA (rs1800497) single nucleotide polymorphism has been associated with reduced striatal DA D2/D3 receptor (D2/D3R) availability. However, radioligands used to estimate D2/D3R are displaceable by endogenous DA and are nonselective for D2R, leaving the relationship between TaqIA genotype and...

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PMID: 27241797
DOI: 10.1002/syn.21916
PMCID: PMC4980198

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DRD2
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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