Article
Histopathological Classification of Cross-Sectional Image-Negative Hyperaldosteronism.
The Journal of clinical endocrinology and metabolism - 1 Apr 2017
Yamazaki Yuto, Nakamura Yasuhiro, Omata Kei, Ise Kazue, Tezuka Yuta, Ono Yoshikiyo, Morimoto Ryo, Nozawa Yukinaga, Gomez-Sanchez Celso E, Tomlins Scott A, Rainey William E, Ito Sadayoshi, Satoh Fumitoshi, Sasano Hironobu
Abstract excerpt
Context: Approximately half of patients with primary aldosteronism (PA) have clinically evident disease according to clinical (hypertension) and/or laboratory (aldosterone and renin levels) findings but do not have nodules detectable in routine cross-sectional imaging. However, the detailed histopathologic, steroidogenic, and pathobiological features of cross-sectional image-negative PA are controversial....
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