Article
Adrenal nodularity and somatic mutations in primary aldosteronism: one node is the culprit?
The Journal of clinical endocrinology and metabolism - 1 Jul 2014
Dekkers T, ter Meer M, Lenders J W M, Hermus A R M, Schultze Kool L, Langenhuijsen J F, Nishimoto K, Ogishima T, Mukai K, Azizan E A B, Tops B, Deinum J, Küsters B
Abstract excerpt
CONTEXT: Somatic mutations in genes that influence cell entry of calcium have been identified in aldosterone-producing adenomas (APAs) of adrenal cortex in primary aldosteronism (PA). Many adrenal glands removed for suspicion of APA do not contain a single adenoma but nodular hyperplasia. OBJECTIVE: The objective of the study was to assess multinodularity and phenotypic and genotypic characteristics of adrenals...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.