Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parallel antibody germline gene and haplotype analyses support the validity of immunoglobulin germline gene inference and discovery.

Molecular immunology - 1 Jul 2017

Kirik Ufuk, Greiff Lennart, Levander Fredrik, Ohlin Mats

Abstract excerpt

Analysis of antibody repertoire development and specific antibody responses important for e.g. autoimmune conditions, allergy, and protection against disease is supported by high throughput sequencing and associated bioinformatics pipelines that describe the diversity of the encoded antibody variable domains. Proper assignment of sequences to germline genes are important for many such processes, for instance in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies
Share to Genes, Immunoglobulin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Immunoglobulin Heavy Chain

Share to Haplotypes

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Multigene Family

Share to Transcriptome

Source

Identifiers

PMID: 28388445
DOI: 10.1016/j.molimm.2017.03.012

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parallel antibody germline gene and haplotype analyses support the validity of immunoglobulin germline gene inference and discovery.PMID 28388445Read ↗

Mosaic deletion patterns of the human antibody heavy chain gene locus as revealed by Bayesian haplotypingSemantic proximity Read ↗

Per-sample immunoglobulin germline inference from B cell receptor deep sequencing dataSemantic proximity Read ↗

Mosaic deletion patterns of the human antibody heavy chain gene locus shown by Bayesian haplotypingSemantic proximity Read ↗

De novo antibody discovery in human blood from full-length single B cell transcriptomics and matching haplotyped-resolved germline assembliesSemantic proximity Read ↗

Ultra-high-throughput IGH genotyping of 25 global populations reveals population-biased allelic diversity and homozygous V and D gene deletions.Semantic proximity Read ↗

Discovery of 10,828 new putative human immunoglobulin heavy chain IGHV variantsSemantic proximity Read ↗

Individual variation in the germline Ig gene repertoire inferred from variable region gene rearrangements.Semantic proximity Read ↗

Reference-Free Germline Immunoglobulin Allele Discovery from B Cell Receptor Sequencing DataSemantic proximity Read ↗

Human IGH germline gene diversity and allele frequencies in 2486 individuals from 25 global populations delineated by ultra-high throughput genotypingSemantic proximity Read ↗

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and NamingSemantic proximity Read ↗

An integrated human immunoglobulin germline resource linking allele diversity to expressed repertoire structureSemantic proximity Read ↗

Population matched (PM) germline allelic variants of immunoglobulin ( <i>IG</i> ) loci: New pmIG database to better understand <i>IG</i> repertoire and selection processes in disease and vaccinationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.