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Article

Insulin/FOXO signaling regulates ovarian prostaglandins critical for reproduction.

Developmental cell - 14 Dec 2010

Edmonds Johnathan W, Prasain Jeevan K, Dorand Dixon, Yang Youfeng, Hoang Hieu D, Vibbert Jack, Kubagawa Homare M, Miller Michael A

Abstract excerpt

Abnormalities in insulin/IGF-1 signaling are associated with infertility, but the molecular mechanisms are not well understood. Here we use liquid chromatography with electrospray ionization tandem mass spectrometry to show that the C. elegans insulin/FOXO pathway regulates the metabolism of loca...

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Identifiers

PMID: 21145501
DOI: 10.1016/j.devcel.2010.11.005
PMCID: PMC3026445

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21145501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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