Article
A new MHC-linked susceptibility locus for primary Sjögren's syndrome: MICA.
Human molecular genetics - 1 Jul 2017
Carapito Raphael, Gottenberg Jacques-Eric, Kotova Irina, Untrau Meiggie, Michel Sandra, Naegely Lydie, Aouadi Ismail, Kwemou Marius, Paul Nicodème, Pichot Angélique, Locke James, Bowman Simon J, Griffiths Bridget, Sivils Kathy L, Sibilia Jean, Inoko Hidetoshi, Micelli-Richard Corinne, Nocturne Gaétane, Ota Masao, Ng Wan-Fai, Mariette Xavier, Bahram Seiamak
Abstract excerpt
The association of primary Sjögren's syndrome (pSS) with Major Histocompatibility Complex (MHC) alleles is quintessential of MHC-disease associations. Indeed, although disease associations with classical HLA class I and II alleles/haplotypes are amply documented, further dissection is often prevented by the strong linkage disequilibrium across the entire MHC complex. Here we study the association of pSS, not with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.