Article
HLA class I and class II are both associated with the genetic predisposition to primary Sjögren syndrome.
Human immunology - 1 Jul 2001
Loiseau P, Lepage V, Djelal F, Busson M, Tamouza R, Raffoux C, Menkes C J, Meyer O, Charron D, Goldberg D
Abstract excerpt
Primary Sjögren syndrome (pSS) is an autoimmune disease characterized by progressive destruction of the exocrine glands leading to mucosal and conjunctival dryness. It is marked by lymphocytic infiltration of the glands and the accumulation of several types of autoantibodies such as rheumatoid factor (RF), antinuclear, anti-SS-A (anti-Ro) and anti-SS-B (anti-LA) autoantibodies. The susceptibility to pSS and/or...
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