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Article

SEEI: spherical evolution with feedback mechanism for identifying epistatic interactions.

BMC genomics - 13 May 2024

Tang De-Yu, Mao Yi-Jun, Zhao Jie, Yang Jin, Li Shi-Yin, Ren Fu-Xiang, Zheng Junxi

Abstract excerpt

BACKGROUND: Detecting epistatic interactions (EIs) involves the exploration of associations among single nucleotide polymorphisms (SNPs) and complex diseases, which is an important task in genome-wide association studies. The EI detection problem is dependent on epistasis models and corresponding optimization methods. Although various models and methods have been proposed to detect EIs, identifying EIs...

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PMID: 38735952
DOI: 10.1186/s12864-024-10373-4
PMCID: PMC11633023

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