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Article

The forgotten woman's cancer: vulvar squamous cell carcinoma (VSCC) and a targeted approach to therapy.

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Sept 2016

Clancy A A, Spaans J N, Weberpals J I

Abstract excerpt

BACKGROUND: The incidence of vulvar squamous cell carcinoma (VSCC) has been on the rise since the 1990s. There has been no new treatment for advanced and recurrent disease in decades, with most women succumbing to the disease. Despite two distinct etiologies of VSCC, human papillomavirus (HPV)-associated and HPV-independent disease, there is no difference in therapeutic options. METHODS: A literature review was...

Topics

Biomarkers, Tumor
Carcinoma, Squamous Cell
Female
Gene Expression Regulation, Neoplastic
Humans
Molecular Targeted Therapy
Mutation
Neoplasm Proteins
Papillomaviridae
Vulvar Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27329249
DOI: 10.1093/annonc/mdw242

Genes

EGFR
PTEN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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