Article
Oncogenic mutations in cervical cancer: genomic differences between adenocarcinomas and squamous cell carcinomas of the cervix.
Cancer - 1 Nov 2013
Wright Alexi A, Howitt Brooke E, Myers Andrea P, Dahlberg Suzanne E, Palescandolo Emanuele, Van Hummelen Paul, MacConaill Laura E, Shoni Melina, Wagle Nikhil, Jones Robert T, Quick Charles M, Laury Anna, Katz Ingrid T, Hahn William C, Matulonis Ursula A, Hirsch Michelle S
Abstract excerpt
BACKGROUND: Cervical cancer is the second leading cause of cancer deaths among women worldwide. The objective of this study was to describe the most common oncogenic mutations in cervical cancers and to explore genomic differences between the 2 most common histologic subtypes: adenocarcinoma and squamous cell carcinoma. METHODS: A high-throughput genotyping platform, termed Oncomap, was used to interrogate 80...
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