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Article

[Complete HBV DNA clone and sequence from serum samples of severe hepatitis B patients].

Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology - 1 Oct 2005

Wu Wei, Li Lan-juan, Chen Yu, Li Jun, Qian Xiang, Cheng Dong-qing

Abstract excerpt

OBJECTIVE: To study the association between hepatitis B virus (HBV) mutants and the pathogenesis of severe hepatitis B by full-length HBV genome. METHODS: Serum samples from 10 severe hepatitis B patients were collected in our hospital. Serum HBV DNAs were extracted using DNA mini Kit, and amplified by LA Taq DNA polymerase to yield full-length HBV DNA. PCR products were isolated and cloned into vector pUCm-T,...

Topics

Adult
B-Lymphocytes
Cloning, Molecular
Epitopes
Genome, Viral
Hepatitis B
Hepatitis B Surface Antigens
Hepatitis B virus
Humans
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Protein Precursors

Sequence Analysis

T-Lymphocytes, Cytotoxic

Source

Identifiers

PMID: 16248943

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