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Article

Characterization and Functional Analysis of Mouse Semi-invariant Natural T Cells.

Current protocols in immunology - 3 Apr 2017

Kumar Amrendra, Bezbradica Jelena S, Stanic Aleksandar K, Joyce Sebastian

Abstract excerpt

Semi-invariant natural killer T (iNKT) cells are CD1d-restricted innate-like lymphocytes that recognize lipid agonists. Activated iNKT cells have immunoregulatory properties. Human and mouse iNKT cell functions elicited by different glycolipid agonists are highly conserved, making the mouse an excellent animal model for understanding iNKT cell biology in vivo. This unit describes basic methods for the...

Topics

Animals
Antigens, Surface
Biomarkers
Flow Cytometry
Immunophenotyping
Lymphocyte Activation
Mice
Natural Killer T-Cells
Phenotype
T-Lymphocyte Subsets

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28369682
DOI: 10.1002/cpim.22

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