Article
CD1d-restricted glycolipid antigens: presentation principles, recognition logic and functional consequences.
Expert reviews in molecular medicine - 7 Jul 2008
Florence William C, Bhat Rakesh K, Joyce Sebastian
Abstract excerpt
Invariant natural killer T (iNKT) cells are innate lymphocytes whose functions are regulated by self and foreign glycolipid antigens presented by the antigen-presenting molecule CD1d. Activation of iNKT cells in vivo results in rapid release of copious amounts of effector cytokines and chemokines with which they regulate innate and adaptive immune responses to pathogens, certain types of cancers and...
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