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Article

Changes in IP3 Receptor Expression and Function in Aortic Smooth Muscle of Atherosclerotic Mice.

Journal of vascular research - 1 Jan 2017

Ewart Marie-Ann, Ugusman Azizah, Vishwanath Anisha, Almabrouk Tarek A M, Alganga Husam, Katwan Omar J, Hubanova Pavlina, Currie Susan, Kennedy Simon

Abstract excerpt

Peroxynitrite is an endothelium-independent vasodilator that induces relaxation via membrane hyperpolarization. The activation of IP3 receptors triggers the opening of potassium channels and hyperpolarization. Previously we found that relaxation to peroxynitrite was maintained during the development of atherosclerosis due to changes in the expression of calcium-regulatory proteins. In this study we investigated:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28365690
DOI: 10.1159/000461581
PMCID: PMC5804831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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