Article
Effect of cerivastatin on endothelial dysfunction and aortic CD36 expression in diabetic hyperlipidemic rats.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Aug 2004
Nakamura Tetsuya, Saito Yuichiro, Ohyama Yoshio, Uchiyama Tsuyoshi, Sumino Hiroyuki, Kurabayashi Masahiko
Abstract excerpt
A mutation of the CD36 gene that encodes a fatty acid transporter has been reported to play a role in insulin resistance in spontaneously hypertensive rat (SHR). Statins reduce circulating cholesterol and triglyceride concentrations. The objective of this study was to determine the role of CD36 and the significance of statin therapy in insulin-resistance syndromes. We determined the isometric relaxation induced...
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