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Article

Associations between sex and lifestyle activities with cognitive reserve in mid-life adults with genetic risk for Alzheimer's disease.

Alzheimer's research & therapy - 13 Nov 2024

Qi Qing, Deng Feng, Sammon Rebecca, Ritchie Karen, Muniz-Terrera Graciela, Koychev Ivan, Malhotra Paresh, Hutchinson Siobhan, Robinson David, O'Brien John T, Ritchie Craig W, Lawlor Brian, Naci Lorina

Abstract excerpt

BACKGROUND: Females have a higher age-adjusted incidence of Alzheimer's Disease (AD) than males, even when accounting for longer lifespan and, therefore, stand to benefit the most from dementia prevention efforts. As exposure to many modifiable risk factors for dementia begins in mid-life, interventions must be implemented from middle-age. Building cognitive reserve, particularly through stimulating avocational...

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PMID: 39533372
DOI: 10.1186/s13195-024-01610-9
PMCID: PMC11559201

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