Article
Memory performance-related dynamic brain connectivity indicates pathological burden and genetic risk for Alzheimer's disease.
Alzheimer's research & therapy - 31 Mar 2017
Quevenco Frances C, Preti Maria G, van Bergen Jiri M G, Hua Jun, Wyss Michael, Li Xu, Schreiner Simon J, Steininger Stefanie C, Meyer Rafael, Meier Irene B, Brickman Adam M, Leh Sandra E, Gietl Anton F, Buck Alfred, Nitsch Roger M, Pruessmann Klaas P, van Zijl Peter C M, Hock Christoph, Van De Ville Dimitri, Unschuld Paul G
Abstract excerpt
BACKGROUND: The incidence of Alzheimer's disease (AD) strongly relates to advanced age and progressive deposition of cerebral amyloid-beta (Aβ), hyperphosphorylated tau, and iron. The purpose of this study was to investigate the relationship between cerebral dynamic functional connectivity and variability of long-term cognitive performance in healthy, elderly subjects, allowing for local pathology and genetic...
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