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Interferon-stimulated gene 20-kDa protein (ISG20) in infection and disease: Review and outlook

1 Jan 2017

Abstract excerpt

Interferon-stimulated exonuclease gene 20 (ISG20) is an RNA exonuclease in the yeast RNA exonuclease 4 homolog (REX4) subfamily and the DEDDh exonuclease family, and this gene codes for a 20-kDa protein. Those exonucleases are involved in cleaving single-stranded RNA and DNA. ISG20 is also referred to as HEM45 (HeLa estrogen-modulated, band 45). Expression of ISG20 can be induced or regulated by both type I and...

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PMID: 28357179
DOI: 10.5582/irdr.2017.01004

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