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Article

Interferon-induced exonuclease ISG20 exhibits an antiviral activity against human immunodeficiency virus type 1.

The Journal of general virology - 1 Aug 2005

Espert Lucile, Degols Geneviève, Lin Yea-Lih, Vincent Thierry, Benkirane Monsef, Mechti Nadir

Abstract excerpt

Interferons (IFNs) encode a family of secreted proteins that provide the front-line defence against viral infections. It was recently shown that ISG20, a new 3'-->5' exoribonuclease member of the DEDD superfamily of exonucleases, represents a novel antiviral pathway in the mechanism of IFN action. In this report, it was shown that ISG20 expression is rapidly and strongly induced during human immunodeficiency...

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Source

Identifiers

PMID: 16033969
DOI: 10.1099/vir.0.81074-0

Genes

ISG20
DEDD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interferon-induced exonuclease ISG20 exhibits an antiviral activity against human immunodeficiency virus type 1.PMID 16033969Read ↗

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