Article
Dependence of cancer risk from environmental exposures on underlying genetic susceptibility: an illustration with polycyclic aromatic hydrocarbons and breast cancer.
British journal of cancer - 25 Apr 2017
Shen Jing, Liao Yuyan, Hopper John L, Goldberg Mandy, Santella Regina M, Terry Mary Beth
Abstract excerpt
BACKGROUND: Most studies of environmental risk factors and breast cancer are conducted using average risk cohorts. METHODS: We examined the association between polycyclic aromatic hydrocarbon (PAH)-albumin adducts in bloods from baseline and breast cancer risk in a prospective nested case-control study (New York site of the BCFR, 80 cases and 156 controls). We estimated the 10-year absolute breast cancer risk by...
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