Article
Testing for Gene-Environment Interactions Using a Prospective Family Cohort Design: Body Mass Index in Early and Later Adulthood and Risk of Breast Cancer.
American journal of epidemiology - 15 Mar 2017
Dite Gillian S, MacInnis Robert J, Bickerstaffe Adrian, Dowty James G, Milne Roger L, Antoniou Antonis C, Weideman Prue, Apicella Carmel, Giles Graham G, Southey Melissa C, Jenkins Mark A, Phillips Kelly-Anne, Win Aung Ko, Terry Mary Beth, Hopper John L
Abstract excerpt
The ability to classify people according to their underlying genetic susceptibility to a disease is increasing with new knowledge, better family data, and more sophisticated risk prediction models, allowing for more effective prevention and screening. To do so, however, we need to know whether risk associations are the same for people with different genetic susceptibilities. To illustrate one way to estimate such...
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