Article
Association between STK11 Gene Polymorphisms and Coronary Artery Disease in Type 2 Diabetes in Han Population in China.
Journal of diabetes research - 1 Jan 2017
Ma Xiaowei, Bai Ge, Lu Difei, Huang Linjuan, Zhang Jianwei, Deng Ruifen, Ding Shan, Gu Nan, Guo Xiaohui
Abstract excerpt
Background. Recent studies indicated that the Serine threonine kinase 11 (STK11), which is a key regulator of the AMP-activated protein kinase (AMPK), plays a crucial role in cardiovascular system. This study aimed to investigate whether genetic variations in the STK11 gene affect the risk of coronary artery disease (CAD) in Chinese type 2 diabetics. Methods. 5 haplotype-tagging single nucleotide polymorphisms...
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