Article
Common variants in adiponectin gene are associated with coronary artery disease and angiographical severity of coronary atherosclerosis in type 2 diabetes.
Cardiovascular diabetology - 17 Apr 2013
Tong Guoxin, Wang Ningfu, Leng Jianhang, Tong Xiaoshan, Shen Yun, Yang Jianmin, Ye Xianhua, Zhou Liang, Zhou Yujie
Abstract excerpt
BACKGROUND: Adiponectin, an adipokine facilitating insulin action, has antiatherogenic effects. This study investigated whether common single nucleotide polymorphisms (SNPs) in the adiponectin gene influenced plasma adiponectin level and whether they were associated with the risk of coronary artery disease (CAD) and its angiographical severity in type 2 diabetes in Chinese population. METHODS: 11 tagging SNPs...
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