Article
Effect of AMP-activated protein kinase subunit alpha 2 (PRKAA2) genetic polymorphisms on susceptibility to type 2 diabetes mellitus and diabetic nephropathy in a Chinese population.
Journal of diabetes - 1 Jan 2018
Li Qingchu, Li Cuilin, Li Haoyun, Zeng Liu, Kang Zhiqiang, Mao Yu, Tang Xinyue, Zheng Panpan, He Li, Luo Fang, Li Zhi
Abstract excerpt
BACKGROUND: It is well known that AMP-activated protein kinase (AMPK) is a key factor affecting the development of type 2 diabetes mellitus (T2DM). The single nucleotide polymorphism (SNP) rs2746342 in the AMPK alpha 2 subunit gene (PRKAA2) has been found to be associated with susceptibility to T2DM in the Chinese Han population. The present study further investigates the association of PRKAA2 genotypes with...
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