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Article

Genetic variants in PCSK1 gene are associated with the risk of coronary artery disease in type 2 diabetes in a Chinese Han population: a case control study.

PloS one - 1 Jan 2014

Wei Xiaowei, Ma Xiaowei, Lu Ran, Bai Ge, Zhang Jianwei, Deng Ruifen, Gu Nan, Feng Nan, Guo Xiaohui

Abstract excerpt

BACKGROUND: Insulin and glucagon-like peptide 1 (GLP-1), converted by proprotein convertase 1 (PC1/3) from proinsulin and proglucagon, are associated with type 2 diabetes (T2DM) and coronary artery disease (CAD). The aim of this study is to investigate the association of PCSK1 gene, which encodes PC1/3, with the risk of CAD in Chinese patients with T2DM. METHODS: We selected and genotyped 5 haplotype-tagging...

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Source

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Identifiers

PMID: 24489861
DOI: 10.1371/journal.pone.0087168
PMCID: PMC3904973

Genes

CAD
PCSK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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