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Article

Synergistic effect of smoking with genetic variants in the AMPKα1 gene on the risk of coronary artery disease in type 2 diabetes.

Diabetes/metabolism research and reviews - 1 Sept 2014

Ma Xiaowei, Zhang Jianwei, Deng Ruifen, Ding Shan, Gu Nan, Guo Xiaohui

Abstract excerpt

BACKGROUND: Increasing evidence suggests that adenosine monophosphate-activated protein kinase (AMPK) plays a critical physiological role in the cardiovascular system. The objective of this study was to assess the possible correlation between the genetic variability of the AMPKα1 (PRKAA1) gene and the risk of cardiovascular disease, as well as the interactive effects of the genetic variations and environmental...

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Identifiers

PMID: 24395629
DOI: 10.1002/dmrr.2520

Genes

PRKAA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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