Article
SNP-sites: rapid efficient extraction of SNPs from multi-FASTA alignments.
Microbial genomics - 1 Apr 2016
Page Andrew J, Taylor Ben, Delaney Aidan J, Soares Jorge, Seemann Torsten, Keane Jacqueline A, Harris Simon R
Abstract excerpt
Rapidly decreasing genome sequencing costs have led to a proportionate increase in the number of samples used in prokaryotic population studies. Extracting single nucleotide polymorphisms (SNPs) from a large whole genome alignment is now a routine task, but existing tools have failed to scale efficiently with the increased size of studies. These tools are slow, memory inefficient and are installed through...
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