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NASP: an accurate, rapid method for the identification of SNPs in WGS datasets that supports flexible input and output formats.

Microbial genomics - 1 Aug 2016

Sahl Jason W, Lemmer Darrin, Travis Jason, Schupp James M, Gillece John D, Aziz Maliha, Driebe Elizabeth M, Drees Kevin P, Hicks Nathan D, Williamson Charles Hall Davis, Hepp Crystal M, Smith David Earl, Roe Chandler, Engelthaler David M, Wagner David M, Keim Paul

Abstract excerpt

Whole-genome sequencing (WGS) of bacterial isolates has become standard practice in many laboratories. Applications for WGS analysis include phylogeography and molecular epidemiology, using single nucleotide polymorphisms (SNPs) as the unit of evolution. NASP was developed as a reproducible method that scales well with the hundreds to thousands of WGS data typically used in comparative genomics applications. In...

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PMID: 28348869
DOI: 10.1099/mgen.0.000074
PMCID: PMC5320593

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NASP

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