Article
prewas: data pre-processing for more informative bacterial GWAS.
Microbial genomics - 1 May 2020
Saund Katie, Lapp Zena, Thiede Stephanie N, Pirani Ali, Snitkin Evan S
Abstract excerpt
While variant identification pipelines are becoming increasingly standardized, less attention has been paid to the pre-processing of variants prior to their use in bacterial genome-wide association studies (bGWAS). Three nuances of variant pre-processing that impact downstream identification of genetic associations include the separation of variants at multiallelic sites, separation of variants in overlapping...
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