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Article

Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae

21 Jul 2015

Abstract excerpt

is a leading cause of invasive pneumococcal disease (IPD) worldwide, with the highest burden in developing countries. We report the whole-genome sequencing analysis of 448 serotype 1 isolates from 27 countries worldwide (including 11 in Africa). The global serotype 1 population shows a strong phylogeographic structure at the continental level, and within Africa there is further region-specific structure. Our...

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PMID: 28348812
DOI: 10.1099/mgen.0.000027

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