Article
Comparative phylogenomics of Streptococcus pneumoniae isolated from invasive disease and nasopharyngeal carriage from West Africans.
BMC genomics - 29 Oct 2012
Donkor Eric S, Stabler Richard A, Hinds Jason, Adegbola Richard A, Antonio Martin, Wren Brendan W
Abstract excerpt
BACKGROUND: We applied comparative phylogenomics (whole genome comparisons of microbes using DNA microarrays combined with Bayesian-based phylogenies) to investigate S. pneumoniae isolates from West Africa, with the aim of providing insights into the pathogenicity and other features related to the biology of the organism. The strains investigated comprised a well defined collection of 58 invasive and carriage...
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