Article
Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013.
Journal of clinical microbiology - 1 May 2016
du Plessis Mignon, Allam Mushal, Tempia Stefano, Wolter Nicole, de Gouveia Linda, von Mollendorf Claire, Jolley Keith A, Mbelle Nontombi, Wadula Jeannette, Cornick Jennifer E, Everett Dean B, McGee Lesley, Breiman Robert F, Gladstone Rebecca A, Bentley Stephen D, Klugman Keith P, von Gottberg Anne
Abstract excerpt
Serotype 1 is an important cause of invasive pneumococcal disease in South Africa and has declined following the introduction of the 13-valent pneumococcal conjugate vaccine in 2011. We genetically characterized 912 invasive serotype 1 isolates from 1989 to 2013. Simpson's diversity index (D) and recombination ratios were calculated. Factors associated with sequence types (STs) were assessed. Clonal complex 217...
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