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Article

Synergistic Expression of Histone Deacetylase 9 and Matrix Metalloproteinase 12 in M4 Macrophages in Advanced Carotid Plaques.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 May 2017

Oksala N K J, Seppälä I, Rahikainen R, Mäkelä K-M, Raitoharju E, Illig T, Klopp N, Kholova I, Laaksonen R, Karhunen P J, Hytönen V P, Lehtimäki T

Abstract excerpt

OBJECTIVE/BACKGROUND: Expression patterns and association with cell specific gene expression signatures of the epigenetic regulator histone deacetylase 9 (HDAC9) and matrix metalloproteinase 12 (MMP12) in human plaque are not known. METHODS: This was a prospective cohort study. Genome wide expression analysis was performed in carotid, femoral, aortic plaques (n = 68) and left internal thoracic (LITA) controls...

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Topics

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Share to Carotid Arteries
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histone Deacetylases

Share to Macrophages

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Share to Microscopy, Confocal

Share to Plaque, Atherosclerotic

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Source

Identifiers

PMID: 28343758
DOI: 10.1016/j.ejvs.2017.02.014

Genes

MMP12
HDAC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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