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Article

Correlations between clinical variables and gene-expression profiles in carotid plaque instability.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery - 1 Dec 2011

Razuvaev A, Ekstrand J, Folkersen L, Agardh H, Markus D, Swedenborg J, Hansson G K, Gabrielsen A, Paulsson-Berne G, Roy J, Hedin U

Abstract excerpt

OBJECTIVE: Strokes, a major cause of disability, are often caused by embolism from unstable carotid plaques. The aim of this study was to validate a biobank of human carotid endarterectomies as a platform for further exploration of pathways for plaque instability. For this purpose, we investigated the relationship between clinical parameters of plaque instability and expression of genes previously shown to be...

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Antigens, Differentiation, Myelomonocytic
Carotid Stenosis
Elastin
Matrix Metalloproteinase 7

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PMID: 21741279
DOI: 10.1016/j.ejvs.2011.05.023

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