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Histone Deacetylases (HDACs) and Atherosclerosis: A Mechanistic and Pharmacological Review

12 Nov 2020

Abstract excerpt

Atherosclerosis (AS), the most common underlying pathology for coronary artery disease, is a chronic inflammatory, proliferative disease in large- and medium-sized arteries. The vascular endothelium is important for maintaining vascular health. Endothelial dysfunction is a critical early event leading to AS, which is a major risk factor for stroke and myocardial infarction. Accumulating evidence has suggested the...

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PMID: 33282862
DOI: 10.3389/fcell.2020.581015

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