Article
HDAC9 Polymorphism Alters Blood Gene Expression in Patients with Large Vessel Atherosclerotic Stroke.
Translational stroke research - 1 Feb 2019
Shroff Natasha, Ander Bradley P, Zhan Xinhua, Stamova Boryana, Liu DaZhi, Hull Heather, Hamade Farah R, Dykstra-Aiello Cheryl, Ng Kwan, Sharp Frank R, Jickling Glen C
Abstract excerpt
The histone deacetylase 9 (HDAC9) polymorphism rs2107595 is associated with an increased risk for large vessel atherosclerotic stroke (LVAS). In humans, there remains a need to better understand this HDAC9 polymorphism's contribution to large vessel stroke. In this pilot study, we evaluated whether the HDAC9 polymorphism rs2107595 is associated with differences in leukocyte gene expression in patients with LVAS....
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