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Article

Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.

Stroke - 1 May 2013

Markus Hugh S, Mäkelä Kari-Matti, Bevan Steve, Raitoharju Emma, Oksala Niku, Bis Joshua C, O'Donnell Chris, Hainsworth Atticus, Lehtimäki Terho

Abstract excerpt

BACKGROUND AND PURPOSE: A novel association between a single nucleotide polymorphism on chromosome 7p21.1 and large-vessel ischemic stroke was recently identified. The most likely underlying gene is histone deacetylase 9 (HDAC9). The mechanism by which HDAC9 increases stroke risk is not clear; bo...

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Source

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Identifiers

PMID: 23449258
DOI: 10.1161/STROKEAHA.111.000217
PMCID: PMC4206941

Genes

HDAC9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23449258-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Evidence HDAC9 genetic variant associated with ischemic stroke increases risk via promoting carotid atherosclerosis.PMID 23449258Read ↗

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