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Article

Quasispecies of Hepatitis C Virus Participate in Cell-Specific Infectivity.

Scientific reports - 22 Mar 2017

Fukuhara Takasuke, Yamamoto Satomi, Ono Chikako, Nakamura Shota, Motooka Daisuke, Mori Hiroyuki, Kurihara Takeshi, Sato Asuka, Tamura Tomokazu, Motomura Takashi, Okamoto Toru, Imamura Michio, Ikegami Toru, Yoshizumi Tomoharu, Soejima Yuji, Maehara Yoshihiko, Chayama Kazuaki, Matsuura Yoshiharu

Abstract excerpt

It is well documented that a variety of viral quasispecies are found in the patients with chronic infection of hepatitis C virus (HCV). However, the significance of quasispecies in the specific infectivity to individual cell types remains unknown. In the present study, we analyzed the role of quasispecies of the genotype 2a clone, JFH1 (HCVcc), in specific infectivity to the hepatic cell lines, Huh7.5.1 and...

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Identifiers

PMID: 28327559
DOI: 10.1038/srep45228
PMCID: PMC5361118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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