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Article

Development of cell culture infectious clones for hepatitis C virus genotype 1b and transcription analysis of 1b-infected hepatoma cells.

Antiviral research - 1 Sept 2021

Li Jinqian, Zhou Qing, Rong Liang, Rong Dade, Yang Yang, Hao Jiawei, Zhang Zhenzhen, Ma Ling, Rao Guirong, Zhou Yuanping, Xiao Fei, Li Chengyao, Wang Haihe, Li Yi-Ping

Abstract excerpt

Globally, hepatitis C virus (HCV) genotype 1b is the most prevalent, and its infection has been found to associate with a higher risk of hepatocellular carcinoma (HCC) than other genotype viruses. However, an efficient infectious HCV genotype 1b culture system is unavailable, which has largely hampered the study of this important genotype virus. In this study, by using a systematic approach combining the...

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PMID: 34252495
DOI: 10.1016/j.antiviral.2021.105136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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