Article
Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency.
Osteoarthritis and cartilage - 1 Jul 2017
Heinonen J, Zhang F-P, Surmann-Schmitt C, Honkala S, Stock M, Poutanen M, Säämänen A-M
Abstract excerpt
OBJECTIVE: The role of Snorc, a novel cartilage specific transmembrane proteoglycan, was studied during skeletal development using two Snorc knockout mouse models. Hypothesizing that Snorc, like the other transmembrane proteoglycans, may be a coreceptor, we also studied its interaction with growth factors. METHODS: Skeletal development was studied in wild type (WT) and Snorc knockout mice during postnatal...
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