Article
Sparc (Osteonectin) functions in morphogenesis of the pharyngeal skeleton and inner ear.
Matrix biology : journal of the International Society for Matrix Biology - 1 Jul 2008
Rotllant Josep, Liu Dong, Yan Yin-Lin, Postlethwait John H, Westerfield Monte, Du Shao-Jun
Abstract excerpt
Sparc (Osteonectin), a matricellular glycoprotein expressed by many differentiated cells, is a major non-collagenous constituent of vertebrate bones. Recent studies indicate that Sparc expression appears early in development, although its function and regulation during embryogenesis are largely unknown. We cloned zebrafish sparc and investigated its role during development, using a mo rpholino antisense...
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