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Article

Gene-based genome-wide association study identified 19p13.3 for lean body mass.

Scientific reports - 21 Mar 2017

Ran Shu, Zhang Lei, Liu Lu, Feng An-Ping, Pei Yu-Fang, Zhang Lei, Han Ying-Ying, Lin Yong, Li Xiao, Kong Wei-Wen, You Xin-Yi, Zhao Wen, Tian Qing, Shen Hui, Zhang Yong-Hong, Deng Hong-Wen

Abstract excerpt

Lean body mass (LBM) is a complex trait for human health. To identify genomic loci underlying LBM, we performed a gene-based genome-wide association study of lean mass index (LMI) in 1000 unrelated Caucasian subjects, and replicated in 2283 unrelated Caucasians subjects. Gene-based association analyses highlighted the significant associations of three genes UQCR, TCF3 and MBD3 in one single locus 19p13.3...

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Source

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Identifiers

PMID: 28322352
DOI: 10.1038/srep45025
PMCID: PMC5359571

Genes

MBD3
TCF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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