Article
Systematical analyses of variants in DNase I hypersensitive sites to identify hepatocellular carcinoma susceptibility loci in a Chinese population.
Journal of gastroenterology and hepatology - 1 Nov 2017
Jiang Tao, Du Fangzhi, Qin Na, Lu Qun, Dai Juncheng, Shen Hongbing, Hu Zhibin
Abstract excerpt
BACKGROUND AND AIM: Although several variants located at coding and non-coding regions were evaluated by previous studies, the evidence for associations between variants located in DNase I-hypersensitive sites (DHSs) and hepatocellular carcinoma (HCC) risk was still limited. Recent advances using ENCODE data indicated that genetic variants in DHSs played an important role in carcinogenesis. Therefore,...
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