Article
Two polymorphisms of USF1 gene (-202G>A and -844C>T) may be associated with hepatocellular carcinoma susceptibility based on a case-control study in Chinese Han population.
Medical oncology (Northwood, London, England) - 1 Dec 2014
Zhou Xu, Zhu Hua-qiang, Ma Chao-qun, Li Hong-guang, Liu Fang-feng, Chang Hong, Lu Jun
Abstract excerpt
Hepatocellular carcinoma (HCC) is a prototype of liver cancer, which is closely related to manifested metabolism of lip and glucose. Upstream transcription factor 1 (USF1) is an important transcription factor in human genome, and it regulates the expression of multiple genes associated with lipid and glucose metabolism. This study aims at investigating the correlation between seven common USF1 polymorphisms...
Topics
- Adult
- Asian People
- Carcinoma, Hepatocellular
- Case-Control Studies
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Humans
- Liver Neoplasms
- Male
- Middle Aged
- Polymorphism, Single Nucleotide
- Population Surveillance