Article
Analysis of mutations in DNA damage repair pathway gene in Chinese patients with hepatocellular carcinoma.
Scientific reports - 19 Jul 2022
Li Jiarong, Li Nianfeng, Azhar Muhammad Salman, Liu Ling, Wang Liheng, Zhang Qi, Sheng Langqing, Wang Jianhua, Feng Sijia, Qiu Qixuan, Xiao Yao
Abstract excerpt
The incidence of hepatocellular carcinoma (HCC) has increased in these years. DNA damage repair (DDR) pathway is required in response to DNA damage Gene mutations in DDR pathway play an important role in different stages of tumorigenesis and development. Based on the importance of DDR pathway in precision therapy of multiple cancers, we analyzed DDR gene mutations in Chinese patients with HCC. The results showed...
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