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Article

Screening for interaction effects in gene expression data.

PloS one - 1 Jan 2017

Castaldi Peter J, Cho Michael H, Liang Liming, Silverman Edwin K, Hersh Craig P, Rice Kenneth, Aschard Hugues

Abstract excerpt

Expression quantitative trait (eQTL) studies are a powerful tool for identifying genetic variants that affect levels of messenger RNA. Since gene expression is controlled by a complex network of gene-regulating factors, one way to identify these factors is to search for interaction effects between genetic variants and mRNA levels of transcription factors (TFs) and their respective target genes. However,...

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Identifiers

PMID: 28301596
DOI: 10.1371/journal.pone.0173847
PMCID: PMC5354413

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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