Article

A Perspective on Interaction Tests in Genetic Association Studies

2015-05-22

Abstract excerpt

The identification of gene-gene and gene-environment interaction in human traits and diseases is an active area of research that generates high expectation, and most often lead to high disappointment. This is partly explained by a misunderstanding of some of the inherent characteristics of interaction effects. Here, I untangle several theoretical aspects of standard regression-based interaction tests in genetic as...

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Literature Corpus work: fa558e21-9628-5103-a82e-83ade56c80b9
DOI: 10.1101/019661

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