Article

A new mechanism for ribosome rescue can recruit RF1 or RF2 to non-stop ribosomes

2018-11-08

Abstract excerpt

Bacterial ribosomes frequently translate to the 3’ end of an mRNA without terminating at an in-frame stop codon. In all bacteria studied to date, these non-stop ribosomes are rescued using trans -translation. In some species, genes required for trans -translation are essential, but other species can survive without trans -translation because they express an alternative ribosome rescue factor, ArfA or ArfB. Fra...

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Literature Corpus work: f78a148e-d47b-5245-8c05-6018df208bae
DOI: 10.1101/465609

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