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Article

Evolution and diversification of the organellar release factor family.

Molecular biology and evolution - 1 Nov 2012

Duarte Isabel, Nabuurs Sander B, Magno Ramiro, Huynen Martijn

Abstract excerpt

Translation termination is accomplished by proteins of the Class I release factor family (RF) that recognize stop codons and catalyze the ribosomal release of the newly synthesized peptide. Bacteria have two canonical RFs: RF1 recognizes UAA and UAG, RF2 recognizes UAA and UGA. Despite that these two release factor proteins are sufficient for de facto translation termination, the eukaryotic organellar RF protein...

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Identifiers

PMID: 22688947
DOI: 10.1093/molbev/mss157
PMCID: PMC3472500

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